Wirkmechanismus
Wie Risperidon
Klinische Studien
Anwendung und Dosierung
Plasmaspiegel
Fachinfo und Nebenwirkungen
Medikamente
Wirkmechanismus
Wie Risperidon
Klinische Studien
Anwendung und Dosierung
Plasmaspiegel
Fachinfo und Nebenwirkungen
Figure 2 Mean (±SD) plasma concentrations versus time profiles for risperidone active moiety during oral risperidone 4 mg treatment (7th dose) and after switching to risperidone ISM 100 mg (PK population).
Notes: Once daily oral risperidone 4 mg was administered for 7 days. An intense oral pharmacokinetic (PK) analysis was conducted at study Day 7 (last day of the oral risperidone treatment) including samples at pre-dose (within 0.5 hours relative to the dose time), 1, 2, 3, 4, 6, 8, and 12 hours, post-dose (black line). Twenty-four hours after the last oral risperidone dose (study Day 8), a single intramuscular dose of Risperidone ISM 100 mg was administered and PK samples were obtained at pre-dose and 12 hours post-dose, as well as at Days 10, 15, 22, 29, and 36 (blue line).